SCHEMBL345588

SCHEMBL345588

Oc1ccc(C23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
GAA P10253 3/20 0.62
POLB P06746 1/20 0.62
GFER P55789 1/20 0.62
EPHX2 P34913 7/20 0.56
NPC1 O15118 1/20 0.53
MAPT P10636 2/20 0.50
RAB9A P51151 1/20 0.49
ESR1 P03372 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
XBP1 P17861 1/20 0.47
CNR2 P34972 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24559531 1.00 LMNA (0.63) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL22644196 1.00 LMNA (0.63) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL20789695 0.91 LMNA (0.50) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL10296837 0.89 ALDH1A1 (0.52) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL2763437 0.88 LMNA (0.77) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL649556 0.87 ESR1 (0.60) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL16364512 0.87 ESR1 (0.60) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL20648576 0.86 MEN1 (0.49) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL28789384 0.85 ESR1 (0.58) LMNAALDH1A1MEN1KMT2AGAA
SCHEMBL17660048 0.85 EPHX2 (0.47) LMNAALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117625082-B PID-resistant functional auxiliary agent preparation method of EVA adhesive film and EVA adhesive film 苏州易昇光学材料股份有限公司 2024-09-06 CN claimed
CN-117624527-B Antioxidant Huang Chuji, preparation method thereof and EVA adhesive film 苏州易昇光学材料股份有限公司 2024-06-21 CN claimed
CN-117801691-B Anti-precipitation EPE co-extrusion packaging adhesive film 苏州易昇光学材料股份有限公司 2024-06-18 CN claimed
CN-114181091-B Synthesis process of adamantane triphenylamine 维思普新材料(苏州)有限公司 2024-06-14 CN claimed
CN-114672147-B Adamantane-containing random anion exchange membrane and preparation method thereof 华侨大学 2024-05-14 CN claimed
CN-117625082-A PID (potential induced degradation) -resistant functional auxiliary agent, preparation method thereof and EVA (ethylene-vinyl acetate) adhesive film 苏州易昇光学材料股份有限公司 2024-03-01 CN claimed
CN-117624527-A Anti-oxidation Huang Chuji, preparation method thereof and EVA adhesive film 苏州易昇光学材料股份有限公司 2024-03-01 CN claimed
CN-117467249-A Anti-irradiation fruit fresh-keeping film and preparation method thereof 台州鸿博辐照科技有限公司 2024-01-30 CN claimed
CN-109923475-B Photosensitive coloring composition, cured product, coloring spacer and image display device 三菱化学株式会社 2022-12-02 CN claimed
CN-114685828-A Adamantyl block type anion exchange membrane and preparation method thereof 华侨大学 2022-07-01 CN claimed
EP-1398401-A2 Method for creating diamond HOKKAIDO UNIVERSITY (JP) 2004-03-17 EP claimed
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-10-02 US claimed
EP-1336597-A1 Hydroxyphenyl adamantanes and process for the production of the same Honshu Chemical Industry Co., Ltd. (JP) 2003-08-20 EP claimed
EP-1327260-A2 SIMPLIFIED METHOD TO PRODUCE NANOPOROUS SILICON-BASED FILMS Honeywell International Inc. (US) 2003-07-16 EP claimed
US-20030077918-A1 Simplified method to produce nanoporous silicon-based films WU HUI-JUNG (US) 2003-04-24 US claimed
US-6495479-B1 COATING WITH SUCH AS TETRAACETOXYSILANE AND A POROGEN, AGING OR CONDENSING IN PRESENCE OF WATER AND HEATING THE GELLED FILM HONEYWELL INTERNATIONAL, INC. 2002-12-17 US claimed
WO-2001086709-A2 SIMPLIFIED METHOD TO PRODUCE NANOPOROUS SILICON-BASED FILMS HONEYWELL INTERNATIONAL INC. (US) 2001-11-15 WO claimed
EP-1103566-A1 Nickel-based catalyst and gas phase polymerization process for polybutadiene UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-05-30 EP claimed
CN-1296984-A Nickel-based catalyst for producing polybutadiene and gas-phase polymerization process thereof UNION CARBIDE CHEM PLASTIC (US) 2001-05-30 CN claimed
US-5851513-A Antiplaque oral composition and method COLGATE PALMOLIVE COMPANY (US) 1998-12-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same CYP8B1, DHPS, P4HA1 LMNA 674/4885ALDH1A1 118/4885MEN1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.