Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503028 | 0.89 | PDE10A (0.47) | HPGDALDH1A1MAPTKMT2AP2RX7 | |
| SCHEMBL6506747 | 0.89 | CA2 (0.48) | HPGDALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL6494454 | 0.83 | HPGD (0.45) | HPGDALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL6502341 | 0.82 | EPHX2 (0.44) | HPGDALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL6495951 | 0.81 | HPGD (0.53) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6494246 | 0.80 | LMNA (0.44) | HPGDALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL6501926 | 0.78 | KMT2A (0.45) | HPGDALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL6503004 | 0.75 | HPGD (0.46) | HPGDMAPTTP53GAALMNA | |
| SCHEMBL6506024 | 0.74 | MAPT (0.47) | HPGDALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL6503133 | 0.74 | LMNA (0.56) | HPGDALDH1A1MAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |