Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506747 | 0.93 | CA2 (0.48) | PDE10ACA2KMT2AROCK2ROCK1 | |
| SCHEMBL6495876 | 0.89 | HPGD (0.44) | PDE10AKMT2AHPGDALDH1A1P2RX7 | |
| SCHEMBL6495951 | 0.85 | HPGD (0.53) | PDE10ACA2KMT2AHPGDALDH1A1 | |
| SCHEMBL6494246 | 0.83 | LMNA (0.44) | PDE10ACA2KMT2AROCK2ROCK1 | |
| SCHEMBL6501926 | 0.81 | KMT2A (0.45) | PDE10ACA2KMT2AROCK2ROCK1 | |
| SCHEMBL6498811 | 0.81 | HPGD (0.48) | PDE10ACA2KMT2AROCK2ROCK1 | |
| SCHEMBL6506024 | 0.78 | MAPT (0.47) | PDE10ACA2KMT2AROCK2ROCK1 | |
| SCHEMBL6502341 | 0.77 | EPHX2 (0.44) | PDE10AKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL6505651 | 0.77 | HPGD (0.49) | PDE10ACA2KMT2AHPGDALDH1A1 | |
| SCHEMBL6494454 | 0.77 | HPGD (0.45) | PDE10AKMT2AHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |