Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | GMNN | O75496 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030610 | 0.92 | CHRM1 (0.42) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| Ether SCHEMBL6495162 | 0.83 | LMNA (0.36) | GPR84TDP1CYP1A2MAPK1LMNA | |
| SCHEMBL2354265 | 0.82 | GPR84 (0.42) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9423042 | 0.79 | GPR84 (0.48) | GPR84CYP1A2MAPK1LMNAGMNN | |
| SCHEMBL2245795 | 0.79 | GPR84 (0.39) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL141330 | 0.77 | MMP12 (0.49) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3280835 | 0.76 | GPR84 (0.60) | GPR84CYP1A2MAPK1LMNAGMNN | |
| SCHEMBL3285285 | 0.76 | GPR84 (0.60) | GPR84CYP1A2MAPK1LMNAGMNN | |
| SCHEMBL31659464 | 0.75 | GPR84 (0.39) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL31571128 | 0.73 | LMNA (0.56) | GPR84CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6909014-B2 | Intermediates for the synthesis of ether compounds | ESPERION THERAPEUTICS, INC. (US) | 2005-06-21 | — | — | US | disclosed |
| US-20040082548-A1 | Intermediates for the synthesis of ether compounds | ESPERION THERAPEUTICS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082548-A1 | Intermediates for the synthesis of ether compounds | GPR119, PC, PPARG | GPR84 212/4885CHRM1 1808/4885AKR1A1 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.