Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503843 | 0.88 | MAPT (0.48) | HPGDGAAHTTMAPTPOLB | |
| SCHEMBL6504802 | 0.86 | HTT (0.55) | HPGDGAAHTTMAPTPOLB | |
| SCHEMBL6495951 | 0.79 | HPGD (0.53) | HPGDGAAHTTMAPTCA2 | |
| SCHEMBL5245244 | 0.78 | CA2 (0.55) | MAPTCA2PPARGPPARDPPARA | |
| SCHEMBL6505651 | 0.76 | HPGD (0.49) | HPGDGAAHTTMAPTCA2 | |
| SCHEMBL13846776 | 0.76 | CA2 (0.69) | GAAMAPTPOLBCA2LMNA | |
| SCHEMBL6497335 | 0.75 | MEN1 (0.53) | HPGDGAAHTTMAPTPOLB | |
| SCHEMBL6498811 | 0.75 | HPGD (0.48) | HPGDGAAHTTMAPTCA2 | |
| SCHEMBL3306757 | 0.75 | HTT (0.76) | HPGDGAAHTTMAPTHDAC1 | |
| SCHEMBL6378019 | 0.75 | PPARG (0.58) | HPGDCA2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |