Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503268 | 0.72 | NPC1 (0.60) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL6496595 | 0.71 | PPARA (0.56) | PPARG | |
| SCHEMBL6503799 | 0.71 | EGLN2 (0.35) | SMN1; SMN2MAPTEGLN2EGLN1 | |
| SCHEMBL6022882 | 0.69 | KMT2A (0.54) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL6495572 | 0.69 | EGLN2 (0.34) | LMNAMAPTEGLN2EGLN1 | |
| SCHEMBL2169418 | 0.69 | PKM (0.57) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL6502680 | 0.68 | CDC7 (0.41) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL6505070 | 0.68 | TRPV1 (0.35) | KMT2AMEN1SMN1; SMN2MAPTP2RX7 | |
| SCHEMBL6449845 | 0.67 | TMPRSS4 (0.55) | KMT2AMEN1POLBLMNASMN1; SMN2 | |
| SCHEMBL6496054 | 0.67 | KDM4E (0.40) | KMT2AMEN1POLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |