Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503799 | 0.83 | EGLN2 (0.35) | ALDH1A1NPC1SMN1; SMN2EGLN2EGLN1 | |
| SCHEMBL6502680 | 0.82 | CDC7 (0.41) | ADORA2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6504635 | 0.78 | MAPT (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7676306 | 0.77 | MAPT (0.42) | ALDH1A1MEN1KMT2AEGLN1KDM4E | |
| SCHEMBL6505584 | 0.77 | DGAT1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6496508 | 0.76 | FFAR2 (0.35) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6495786 | 0.75 | NPC1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6495572 | 0.75 | EGLN2 (0.34) | ALDH1A1NPC1EGLN2EGLN1MAPT | |
| SCHEMBL6496054 | 0.74 | KDM4E (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7684255 | 0.74 | SHMT1 (0.40) | ALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |