Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505070 | 0.82 | TRPV1 (0.35) | NPC1RAB9ASMN1; SMN2EGLN2EGLN1 | |
| SCHEMBL6503799 | 0.81 | EGLN2 (0.35) | NPC1SMN1; SMN2EGLN2EGLN1TP53 | |
| SCHEMBL6504635 | 0.81 | MAPT (0.47) | HPGDSMN1; SMN2LMNATP53MAPT | |
| SCHEMBL6495548 | 0.79 | TP53 (0.40) | HPGDSMN1; SMN2TP53MAPTMEN1 | |
| SCHEMBL6496866 | 0.79 | MAPT (0.40) | NPC1SMN1; SMN2TP53MAPTPPARA | |
| SCHEMBL7676306 | 0.79 | MAPT (0.42) | HPGDEGLN1LMNATP53MAPT | |
| SCHEMBL6495786 | 0.78 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL6495572 | 0.76 | EGLN2 (0.34) | NPC1EGLN2EGLN1LMNATP53 | |
| SCHEMBL6496054 | 0.75 | KDM4E (0.40) | NPC1HPGDRAB9ASMN1; SMN2TP53 | |
| SCHEMBL6505584 | 0.75 | DGAT1 (0.38) | NPC1HPGDRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |