Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503799 | 0.91 | EGLN2 (0.35) | EGLN2EGLN1CSNK2A2CSNK2A1HDAC3 | |
| SCHEMBL6502680 | 0.76 | CDC7 (0.41) | EGLN2EGLN1HDAC3HDAC1HDAC6 | |
| SCHEMBL6504635 | 0.75 | MAPT (0.47) | TP53ALDH1A1MAPTLMNA | |
| SCHEMBL6505070 | 0.75 | TRPV1 (0.35) | EGLN2EGLN1ALDH1A1NPC1MAPT | |
| SCHEMBL7676306 | 0.74 | MAPT (0.42) | EGLN1TP53ALDH1A1MAPTLMNA | |
| SCHEMBL6495569 | 0.73 | PPARA (0.46) | — | |
| SCHEMBL6495707 | 0.70 | L3MBTL1 (0.44) | L3MBTL1HDAC3HDAC1HDAC6ALDH1A1 | |
| SCHEMBL6505584 | 0.69 | DGAT1 (0.38) | L3MBTL1TP53ALDH1A1NPC1MAPT | |
| SCHEMBL6495786 | 0.69 | NPC1 (0.38) | TP53ALDH1A1NPC1LMNA | |
| SCHEMBL6496601 | 0.69 | KMT2A (0.48) | EGLN2EGLN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |