Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 6/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 12/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6504858 | 0.90 | HPGD (0.40) | PPARGPPARA | |
| SCHEMBL6497497 | 0.90 | S1PR3 (0.38) | S1PR3LNPEPHRH3 | |
| Trifluoroacetic Acid SCHEMBL6498995 | 0.87 | PPARG (0.39) | PPARGPPARA | |
| Trifluoroacetic Acid SCHEMBL6505054 | 0.86 | HPGD (0.49) | PPARGPPARA | |
| SCHEMBL6503457 | 0.81 | PDE4A (0.42) | S1PR3PPARGPPARAHRH3 | |
| SCHEMBL6506584 | 0.80 | PPARA (0.46) | PPARGPPARA | |
| SCHEMBL6503062 | 0.80 | PDE4A (0.40) | S1PR3PPARGPPARAHRH3 | |
| SCHEMBL6502859 | 0.79 | S1PR3 (0.36) | S1PR3PPARGPPARAHRH3 | |
| SCHEMBL6504861 | 0.79 | HPGD (0.39) | — | |
| SCHEMBL6505315 | 0.79 | PPARG (0.46) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |