Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504861 | 0.90 | HPGD (0.39) | MEN1KMT2AHPGDRAB9AEPHX2 | |
| Trifluoroacetic Acid SCHEMBL6497487 | 0.90 | S1PR3 (0.40) | S1PR3HRH3LNPEP | |
| SCHEMBL6499003 | 0.87 | HPGD (0.37) | S1PR3MEN1KMT2AHPGDRAB9A | |
| SCHEMBL6505057 | 0.87 | HPGD (0.48) | KMT2AHPGDRAB9AEPHX2P2RX7 | |
| Trifluoroacetic Acid SCHEMBL6504858 | 0.79 | HPGD (0.40) | HPGDRAB9AP2RX7 | |
| Trifluoroacetic Acid SCHEMBL6498995 | 0.76 | PPARG (0.39) | HPGDRAB9A | |
| Trifluoroacetic Acid SCHEMBL6505054 | 0.76 | HPGD (0.49) | KMT2AHPGDRAB9AEPHX2P2RX7 | |
| SCHEMBL6504395 | 0.74 | PPARA (0.37) | P2RX7WDR5 | |
| SCHEMBL6505593 | 0.74 | ADORA2A (0.35) | HPGDRAB9A | |
| SCHEMBL6494741 | 0.74 | PPARA (0.39) | MEN1KMT2AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |