Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.39 |
| ▸ | PPARA | Q07869 | 12/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6504858 | 0.92 | HPGD (0.40) | PPARGPPARAPPARDHPGDRAB9A | |
| SCHEMBL6499003 | 0.89 | HPGD (0.37) | PPARGPPARAPPARDHPGDRAB9A | |
| Trifluoroacetic Acid SCHEMBL6505054 | 0.88 | HPGD (0.49) | PPARGPPARAPPARDHPGDRAB9A | |
| Trifluoroacetic Acid SCHEMBL6497487 | 0.87 | S1PR3 (0.40) | PPARGPPARA | |
| SCHEMBL6504955 | 0.81 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6504861 | 0.81 | HPGD (0.39) | HPGDRAB9AALDH1A1TP53NPC1 | |
| SCHEMBL6502816 | 0.80 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6507629 | 0.80 | PPARA (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6504997 | 0.78 | TP53 (0.40) | PPARGPPARAPPARDACACBALDH1A1 | |
| SCHEMBL5553542 | 0.77 | PPARG (0.40) | PPARGPPARAPPARDRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |