Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6504858 | 0.91 | HPGD (0.40) | HPGDRAB9AP2RX7PPARAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6498995 | 0.88 | PPARG (0.39) | HPGDRAB9APPARAALDH1A1PPARG | |
| SCHEMBL6505057 | 0.88 | HPGD (0.48) | HPGDRAB9AKMT2AP2RX7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL6497487 | 0.86 | S1PR3 (0.40) | PPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL6495816 | 0.85 | SHMT1 (0.44) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6504387 | 0.82 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL6502863 | 0.80 | TMEM97 (0.47) | HPGDRAB9AKMT2APPARAALDH1A1 | |
| SCHEMBL6504861 | 0.80 | HPGD (0.39) | HPGDRAB9AKMT2AP2RX7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL6498705 | 0.79 | PPARA (0.37) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6505587 | 0.79 | PPARA (0.38) | HPGDPPARAALDH1A1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |