Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 15/20 | 0.39 |
| ▸ | PPARG | P37231 | 14/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6498995 | 0.92 | PPARG (0.39) | HPGDRAB9APPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6505054 | 0.91 | HPGD (0.49) | HPGDRAB9APPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6497487 | 0.90 | S1PR3 (0.40) | PPARAPPARG | |
| SCHEMBL6504861 | 0.88 | HPGD (0.39) | HPGDRAB9AP2RX7PTGDRALDH1A1 | |
| SCHEMBL6499003 | 0.81 | HPGD (0.37) | HPGDRAB9APPARAPPARGPPARD | |
| SCHEMBL6505057 | 0.80 | HPGD (0.48) | HPGDRAB9AP2RX7 | |
| SCHEMBL6497497 | 0.79 | S1PR3 (0.38) | HPGDRAB9AP2RX7 | |
| SCHEMBL6505285 | 0.79 | PPARA (0.43) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6504387 | 0.78 | PPARA (0.42) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6505587 | 0.78 | PPARA (0.38) | HPGDPPARAPPARGPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| WO-2005007156-A1 | COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE | PHARMACIA CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |