Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991493 | 0.82 | ADORA2A (0.33) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL3211179 | 0.77 | NOTUM (0.35) | MEN1KMT2ALMNAHSD17B10MAPT | |
| SCHEMBL8801367 | 0.75 | DAO (0.37) | PDE4DLMNAALDH1A1 | |
| SCHEMBL7911441 | 0.74 | MAT2A (0.31) | LMNA | |
| SCHEMBL28823378 | 0.74 | ALDH1A1 (0.39) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL8305450 | 0.72 | ALDH1A1 (0.35) | LMNAALDH1A1 | |
| SCHEMBL8801439 | 0.70 | MAT2A (0.31) | LMNA | |
| SCHEMBL8768659 | 0.66 | KDM4E (0.35) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL6228685 | 0.63 | MAPK1 (0.41) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL8801755 | 0.63 | LMNA (0.33) | LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009704-A1 | Substituted aryl ketones | SCHALLNER OTTO (DE) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009704-A1 | Substituted aryl ketones | CBR3, CBR1, CYCS | PDE4A 3689/4885PDE4B 3896/4885PDE4C 3685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.