SCHEMBL8801439

SCHEMBL8801439

CCOc1n[nH]c(=O)n1OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.31
NOTUM Q6P988 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911441 0.85 MAT2A (0.31) MAT2ANOTUMLMNA
SCHEMBL3211179 0.77 NOTUM (0.35) MAT2ANOTUMLMNA
SCHEMBL8801367 0.76 DAO (0.37) MAT2ANOTUMLMNA
SCHEMBL8305450 0.76 ALDH1A1 (0.35) MAT2ANOTUMLMNA
SCHEMBL7991493 0.76 ADORA2A (0.33) MAT2ANOTUMLMNA
SCHEMBL8801755 0.74 LMNA (0.33) LMNA
SCHEMBL3934691 0.73 MTNR1B (0.32)
SCHEMBL6497619 0.70 PDE4A (0.35) LMNA
SCHEMBL8621897 0.70
SCHEMBL5407633 0.69 MEN1 (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP disclosed
US-9981940-B2 Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-05-29 US disclosed
US-20160145235-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-26 US disclosed
EP-3010893-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-04-27 EP disclosed
WO-2014202510-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2014-12-24 WO disclosed
EP-0534266-B1 Sulfonylaminocarbonyltriazolones with two through oxygen bonded substituents BAYER AG (DE) 1997-05-28 EP disclosed
US-5631380-A CHEMICAL INTERMEDIATES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-20 US disclosed
US-5554761-A Herbicidal sulphonylaminocarbonyltriazolinones having two substituents bonded via oxygen BAYER AKTIENGESELLSCHAFT (DE) 1996-09-10 US disclosed
US-5488028-A PLANT GROWTH REGULATORS AND ANTIGROWTH AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1996-01-30 US disclosed
US-5300480-A Pre- and postemergent BAYER AKTIENGESELLSCHAFT (DE) 1994-04-05 US disclosed
EP-0534266-A1 Sulfonylaminocarbonyltriazolones with two through oxygen bonded substituents BAYER AG (DE) 1993-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160145235-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES ARSA, SQOR, AHR MAT2A 335/4885NOTUM 505/4885LMNA 4703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.