SCHEMBL6497788

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27988934	0.91	BCL2L1 (0.48)	BCL2L1BADNOTUMMCL1HSD17B10
	SCHEMBL21938180	0.87	BCL2L1 (0.54)	BCL2L1BADNOTUMHSD17B10GPR35
	SCHEMBL6802081	0.85	MCL1 (0.53)	NOTUMMCL1HSD17B10KDM4EALDH1A1
	SCHEMBL12149327	0.85	BCL2L1 (0.52)	BCL2L1BADNOTUMHSD17B10GPR35
	SCHEMBL6500060	0.83	ALDH1A1 (0.51)	MCL1ALDH1A1DHFRACMSD
	SCHEMBL6497146	0.82	NPC1 (0.53)	NOTUMMCL1HSD17B10KDM4EALDH1A1
	SCHEMBL24183987	0.81	MCL1 (0.61)	MCL1HSD17B10KDM4EALDH1A1MEN1
	SCHEMBL6799953	0.81	RXRA (0.55)	HSD17B10KDM4EALDH1A1USP2HPGD
	SCHEMBL6492370	0.81	HSD17B10 (0.51)	BCL2L1BADNOTUMMCL1HSD17B10
	SCHEMBL6500578	0.81	HDAC7 (0.51)	BCL2L1BADNOTUMMCL1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.