Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499928 | 1.00 | PRCP (0.52) | PRCPELANETMEM97SIGMAR1NPSR1 | |
| SCHEMBL4278572 | 0.85 | PDK1 (0.53) | PRCPELANETMEM97SIGMAR1 | |
| SCHEMBL23533378 | 0.83 | SIGMAR1 (0.46) | PRCPELANETMEM97SIGMAR1 | |
| SCHEMBL6141635 | 0.82 | FKBP1A (0.51) | TMEM97SIGMAR1NPSR1PREPTSHR | |
| SCHEMBL15298942 | 0.82 | FKBP1A (0.51) | TMEM97SIGMAR1NPSR1PREPTSHR | |
| SCHEMBL8487526 | 0.81 | SMN1; SMN2 (0.54) | NPSR1PREPMMP1MMP3MMP7 | |
| SCHEMBL18851102 | 0.80 | DRD2 (0.49) | SIGMAR1NPSR1FKBP1A | |
| SCHEMBL2300448 | 0.80 | POLB (0.52) | NPSR1PREPALDH1A1FKBP1A | |
| SCHEMBL1864842 | 0.80 | POLB (0.52) | NPSR1PREPALDH1A1FKBP1A | |
| SCHEMBL7802196 | 0.80 | POLB (0.52) | NPSR1PREPALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911442-B1 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-06-28 | — | — | US | disclosed |
| EP-1187828-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-21 | — | — | EP | disclosed |