Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499869 | 0.94 | ACKR3 (0.58) | MEN1KMT2AMCHR1POLBACKR3 | |
| SCHEMBL6503729 | 0.87 | EPHX2 (0.58) | MEN1KMT2AMCHR1RAB9ATSHR | |
| SCHEMBL6503460 | 0.85 | SIGMAR1 (0.52) | OPRM1OPRK1ACKR3TMEM97SIGMAR1 | |
| SCHEMBL6505559 | 0.81 | EPHX2 (0.56) | KMT2AACKR3RAB9ATSHRHSD17B10 | |
| SCHEMBL6500610 | 0.80 | GAA (0.59) | MEN1KMT2ATSHRHSD17B10FFAR1 | |
| SCHEMBL6505391 | 0.80 | TSHR (0.52) | MEN1KMT2AMCHR1TSHRHSD17B10 | |
| SCHEMBL6499688 | 0.80 | CYP1A2 (0.56) | MEN1KMT2ARAB9ATSHRHSD17B10 | |
| SCHEMBL6508701 | 0.78 | KDM4E (0.50) | MEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL12438386 | 0.77 | POLB (0.84) | MCHR1POLBTMEM97SIGMAR1TSHR | |
| SCHEMBL9363810 | 0.77 | POLB (0.84) | MCHR1POLBTMEM97SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | MEN1 3088/4885KMT2A 4477/4885MCHR1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.