Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507792 | 0.94 | MTNR1A (0.51) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6498720 | 0.91 | BCHE (0.59) | TSHRHSD17B10KMT2ABCHEACHE | |
| SCHEMBL6503729 | 0.88 | EPHX2 (0.58) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6504830 | 0.86 | BCHE (0.54) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6498806 | 0.85 | ACHE (0.50) | KDM4EMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL6499688 | 0.85 | CYP1A2 (0.56) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6500610 | 0.85 | GAA (0.59) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6507435 | 0.85 | RAB9A (0.49) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL6500080 | 0.82 | CCR8 (0.50) | KDM4EBCHEACHE | |
| SCHEMBL6505559 | 0.82 | EPHX2 (0.56) | TSHRHSD17B10KMT2ABCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | KDM4E 4617/4885TSHR 3179/4885HSD17B10 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.