Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.58 |
| ▸ | LTA4H | P09960 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505559 | 0.94 | EPHX2 (0.56) | EPHX2LTA4HTSHRHSD17B10RAB9A | |
| SCHEMBL6504830 | 0.88 | BCHE (0.54) | EPHX2LTA4HTSHRHSD17B10ALDH1A1 | |
| SCHEMBL6508701 | 0.88 | KDM4E (0.50) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6498560 | 0.87 | MEN1 (0.62) | TSHRHSD17B10RAB9AMEN1KMT2A | |
| SCHEMBL6498720 | 0.85 | BCHE (0.59) | TSHRHSD17B10KMT2AACHEBCHE | |
| SCHEMBL6499418 | 0.85 | APP (0.46) | EPHX2LTA4HRAB9AACHEBCHE | |
| SCHEMBL6500610 | 0.83 | GAA (0.59) | TSHRHSD17B10MEN1KMT2APTGES | |
| SCHEMBL6499688 | 0.83 | CYP1A2 (0.56) | TSHRHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL6507435 | 0.83 | RAB9A (0.49) | TSHRHSD17B10RAB9AALDH1A1MEN1 | |
| SCHEMBL6499395 | 0.83 | BCHE (0.56) | EPHX2LTA4HTSHRHSD17B10BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | EPHX2 796/4885LTA4H 197/4885TSHR 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.