Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 2/20 | 0.44 |
| ▸ | MTTP | P55157 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491092 | 0.93 | CYP3A4 (0.38) | GCGRKDM4ENPC1CYP3A4RAB9A | |
| SCHEMBL6491047 | 0.87 | APOB (0.44) | APOBMTTPGCGRSMN1; SMN2KDM4E | |
| SCHEMBL6501858 | 0.87 | GCGR (0.43) | GCGRSMN1; SMN2KDM4EHSD17B10NPC1 | |
| SCHEMBL6488636 | 0.86 | APOB (0.48) | APOBMTTPGCGRSMN1; SMN2KDM4E | |
| SCHEMBL6492299 | 0.85 | APOB (0.39) | APOBMTTPGCGRSMN1; SMN2KDM4E | |
| SCHEMBL6792786 | 0.84 | KMT2A (0.44) | SMN1; SMN2KDM4EHSD17B10NPC1LMNA | |
| SCHEMBL6500248 | 0.82 | APOB (0.45) | APOBMTTPKDM4ELMNATP53 | |
| SCHEMBL6499324 | 0.82 | POLB (0.41) | APOBMTTPGCGRSMN1; SMN2KDM4E | |
| SCHEMBL6500238 | 0.81 | GCGR (0.44) | APOBMTTPGCGRSMN1; SMN2KDM4E | |
| SCHEMBL6487631 | 0.81 | NR3C1 (0.41) | APOBMTTPGCGRHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | APOB 1/4885MTTP 677/4885GCGR 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.