Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501858 | 0.92 | GCGR (0.43) | KMT2AALDH1A1NPC1RAB9APOLB | |
| SCHEMBL6792292 | 0.91 | ALDH1A1 (0.41) | ALDH1A1LTB4R2NPC1RAB9ACHRNB2 | |
| SCHEMBL6491092 | 0.91 | CYP3A4 (0.38) | KMT2AALDH1A1NPC1RAB9APOLB | |
| SCHEMBL6796239 | 0.91 | GAA (0.55) | KMT2AALDH1A1LTB4R2NPC1RAB9A | |
| SCHEMBL6503623 | 0.88 | MTTP (0.40) | NPC1RAB9AKDM4ECYP3A4CASP3 | |
| SCHEMBL6498587 | 0.84 | APOB (0.44) | NPC1RAB9AKDM4ECYP3A4LMNA | |
| SCHEMBL6788446 | 0.83 | KMT2A (0.46) | KMT2AALDH1A1NPC1RAB9ACHRNB2 | |
| SCHEMBL6793528 | 0.81 | NR3C1 (0.41) | KMT2AALDH1A1LTB4R2NPC1CHRNB2 | |
| SCHEMBL6794600 | 0.81 | L3MBTL1 (0.44) | KMT2AALDH1A1NPC1RAB9ACHRNB2 | |
| SCHEMBL6794499 | 0.80 | CYP3A4 (0.40) | KMT2AALDH1A1LTB4R2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | KMT2A 2457/4885ALDH1A1 1427/4885LTB4R2 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.