Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.37 |
| ▸ | PPARG | P37231 | 14/20 | 0.37 |
| ▸ | PPARD | Q03181 | 9/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6504387 | 0.93 | PPARA (0.42) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6505042 | 0.90 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL6498709 | 0.90 | CDK2 (0.34) | PPARAPPARDCDK2GSK3B | |
| Trifluoroacetic Acid SCHEMBL6531504 | 0.89 | PPARA (0.40) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6494737 | 0.88 | PPARA (0.44) | PPARAPPARGPPARDGSK3B | |
| Trifluoroacetic Acid SCHEMBL6495816 | 0.87 | SHMT1 (0.44) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6505587 | 0.86 | PPARA (0.38) | PPARAPPARGPPARD | |
| SCHEMBL6504395 | 0.82 | PPARA (0.37) | PPARAPPARGPPARDCDK2GSK3B | |
| Trifluoroacetic Acid SCHEMBL6503592 | 0.82 | KDM4E (0.37) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6499170 | 0.81 | ADORA2A (0.39) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |