Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | PPARD | Q03181 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6505587 | 0.90 | PPARA (0.38) | ADORA2AADORA1ALDH1A1HPGDPPARA | |
| Trifluoroacetic Acid SCHEMBL6531504 | 0.90 | PPARA (0.40) | PPARAPPARDPPARGMAPT | |
| SCHEMBL6499174 | 0.90 | ADORA1 (0.38) | ADORA2AADORA1ALDH1A1HPGDHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6494737 | 0.87 | PPARA (0.44) | PPARAPPARDPPARG | |
| Trifluoroacetic Acid SCHEMBL6505042 | 0.86 | PPARA (0.42) | ALDH1A1HPGDKDM4EPPARAPPARD | |
| Trifluoroacetic Acid SCHEMBL6495816 | 0.85 | SHMT1 (0.44) | KDM4EPPARAPPARDPPARGMAPT | |
| Trifluoroacetic Acid SCHEMBL6503592 | 0.85 | KDM4E (0.37) | ALDH1A1KDM4EPPARAPPARDPPARG | |
| Trifluoroacetic Acid SCHEMBL6504387 | 0.84 | PPARA (0.42) | PPARAPPARDPPARG | |
| Trifluoroacetic Acid SCHEMBL6498705 | 0.81 | PPARA (0.37) | PPARAPPARDPPARG | |
| SCHEMBL6531507 | 0.80 | PARP1 (0.36) | ADORA2AALDH1A1HPGDKDM4EPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |