Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.40 |
| ▸ | PPARG | P37231 | 15/20 | 0.40 |
| ▸ | PPARD | Q03181 | 10/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6505042 | 0.94 | PPARA (0.42) | PPARAPPARGPPARDSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6504387 | 0.93 | PPARA (0.42) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6494737 | 0.92 | PPARA (0.44) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6505587 | 0.90 | PPARA (0.38) | PPARAPPARGPPARDCYP1A2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6499170 | 0.90 | ADORA2A (0.39) | PPARAPPARGPPARDMAPT | |
| Trifluoroacetic Acid SCHEMBL6503592 | 0.90 | KDM4E (0.37) | PPARAPPARGPPARD | |
| SCHEMBL6531507 | 0.89 | PARP1 (0.36) | PPARAPPARGPPARDCYP1A2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6498705 | 0.89 | PPARA (0.37) | PPARAPPARGPPARD | |
| Trifluoroacetic Acid SCHEMBL6495816 | 0.86 | SHMT1 (0.44) | PPARAPPARGPPARDMAPT | |
| SCHEMBL6505045 | 0.83 | SMN1; SMN2 (0.35) | PPARAPPARGPPARDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |