Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492074 | 0.87 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MCL1KMT2APTPN11 | |
| SCHEMBL6489327 | 0.85 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MCL1KMT2APTPN11 | |
| SCHEMBL6490238 | 0.85 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2APTPN11HSD17B10SLC6A4 | |
| SCHEMBL6489788 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MCL1KMT2APTPN11 | |
| SCHEMBL6487707 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2MCL1PTPN11HSD17B10 | |
| SCHEMBL31586500 | 0.79 | HSD17B10 (0.58) | ALDH1A1SMN1; SMN2KMT2AHSD17B10DHODH | |
| SCHEMBL6498591 | 0.79 | HSD17B10 (0.58) | ALDH1A1SMN1; SMN2KMT2AHSD17B10DHODH | |
| SCHEMBL6489261 | 0.79 | HSD17B10 (0.47) | ALDH1A1SMN1; SMN2KMT2AHSD17B10RXRA | |
| SCHEMBL8984342 | 0.78 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MCL1KMT2AFFAR4 | |
| SCHEMBL8476474 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MCL1KMT2AFFAR4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | ALDH1A1 1603/4885SMN1; SMN2 1921/4885MCL1 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.