Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EIF4E | P06730 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20509052 | 0.86 | SCN9A (0.44) | MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL6490473 | 0.86 | AKR1C2 (0.49) | HSD17B10SMN1; SMN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6499038 | 0.85 | FOLH1 (0.53) | HSD17B10SMN1; SMN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6488790 | 0.84 | AKR1C3 (0.58) | HSD17B10SMN1; SMN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6498591 | 0.81 | HSD17B10 (0.58) | HSD17B10SMN1; SMN2EIF4EDHODHGPR35 | |
| SCHEMBL31586500 | 0.81 | HSD17B10 (0.58) | HSD17B10SMN1; SMN2EIF4EDHODHGPR35 | |
| SCHEMBL29898486 | 0.80 | PRKAB2 (0.56) | HSD17B10SMN1; SMN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7245003 | 0.79 | PRKAB2 (0.50) | HSD17B10SMN1; SMN2EIF4EPRKAB2PRKAG1 | |
| SCHEMBL6499746 | 0.79 | ALDH1A1 (0.59) | HSD17B10SMN1; SMN2DHODHCYP2C19CYP2C9 | |
| SCHEMBL6492370 | 0.79 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2EIF4EDHODHGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | HSD17B10 901/4885SMN1; SMN2 1921/4885EIF4E 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.