Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505023 | 0.83 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL6499914 | 0.81 | CYP4F2 (0.55) | ALDH1A1 | |
| SCHEMBL27608519 | 0.80 | TYR (0.61) | TYRSPRCHRM2CHRM1CHRM3 | |
| SCHEMBL2385123 | 0.77 | ALDH1A1 (0.66) | TYRSPRCHRM2CHRM1CHRM3 | |
| SCHEMBL6531947 | 0.77 | DRD2 (0.37) | TYRSPROPRM1OPRD1OPRK1 | |
| SCHEMBL6501058 | 0.75 | OPRM1 (0.47) | TYRSPROPRM1OPRD1OPRK1 | |
| SCHEMBL6507161 | 0.74 | RARB (0.46) | ALDH1A1 | |
| SCHEMBL6506348 | 0.74 | KMT2A (0.40) | ALDH1A1TAAR1 | |
| SCHEMBL27665429 | 0.72 | SPR (0.44) | TYRSPROPRM1OPRD1OPRK1 | |
| SCHEMBL104012 | 0.72 | OPRK1 (0.70) | OPRM1OPRD1OPRK1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |