Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984070 | 0.90 | DRD2 (0.35) | HTR1DBRD4APP | |
| SCHEMBL6494165 | 0.88 | HTR1D (0.46) | HTR1DAPP | |
| SCHEMBL6493513 | 0.88 | HTR1D (0.46) | HTR1DAPP | |
| SCHEMBL6984714 | 0.82 | HTR6 (0.35) | — | |
| SCHEMBL6497792 | 0.79 | HTR1D (0.36) | HTR1DBRD4 | |
| SCHEMBL6983290 | 0.78 | DRD2 (0.35) | HTR1DAPP | |
| SCHEMBL6977809 | 0.78 | DRD2 (0.51) | HTR1D | |
| SCHEMBL7134574 | 0.78 | SLC6A4 (0.45) | HTR1D | |
| SCHEMBL6980903 | 0.76 | CTSS (0.40) | APP | |
| SCHEMBL6498042 | 0.74 | HTR1D (0.47) | HTR1DAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844338-B2 | Piperidyindoles as serotonin receptor ligands | ELI LILLY AND COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030225068-A1 | Piperidyindoles as serotonin receptor ligands | ELI LILLY AND COMPANY | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225068-A1 | Piperidyindoles as serotonin receptor ligands | CNR1, HTR1D, HTR1A | HTR1D 2/4885BRD4 2847/4885APP 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.