Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 6/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503216 | 0.80 | TDO2 (0.50) | HTR1DHTR2AHTR1BTDO2SLC6A4 | |
| SCHEMBL21714635 | 0.73 | HTR2A (0.51) | HTR2ASLC6A4 | |
| SCHEMBL6491562 | 0.72 | AR (0.40) | HTR1DHTR2AARMAPTKDM4E | |
| SCHEMBL6499646 | 0.69 | SLC6A4 (0.39) | HTR1DHTR1BMAPTSLC6A4KDM4E | |
| SCHEMBL6492320 | 0.68 | HTR1D (0.37) | HTR1DHTR2AAR | |
| SCHEMBL6492415 | 0.67 | AR (0.42) | HTR1DHTR2AAR | |
| SCHEMBL6502167 | 0.67 | TDO2 (0.45) | HTR1DHTR2AHTR1BTDO2SLC6A4 | |
| SCHEMBL31358064 | 0.65 | HTR2A (0.49) | HTR1DHTR2A | |
| SCHEMBL6812096 | 0.64 | HTR2C (0.55) | HTR1DHTR2AARMAPTKDM4E | |
| SCHEMBL25417441 | 0.63 | PDK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844338-B2 | Piperidyindoles as serotonin receptor ligands | ELI LILLY AND COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030225068-A1 | Piperidyindoles as serotonin receptor ligands | ELI LILLY AND COMPANY | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225068-A1 | Piperidyindoles as serotonin receptor ligands | CNR1, HTR1D, HTR1A | HTR1D 2/4885HTR2A 24/4885AR 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.