Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546220 | 0.79 | HSD17B1 (0.60) | KIF11ARHSD17B1HSD17B2MMP3 | |
| SCHEMBL26373459 | 0.78 | KIF11 (0.46) | LDHAKIF11HDAC6AR | |
| SCHEMBL28678059 | 0.78 | KIF11 (0.46) | LDHAKIF11HDAC6AR | |
| SCHEMBL28674664 | 0.78 | KIF11 (0.46) | LDHAKIF11HDAC6 | |
| Benzene SCHEMBL29148570 | 0.78 | CA2 (0.74) | CRHBPCRHR2CA1CA2 | |
| SCHEMBL426214 | 0.78 | CA2 (0.74) | CRHBPCRHR2CA1CA2 | |
| SCHEMBL1864159 | 0.77 | CNR2 (0.39) | CRHBPCRHR2LDHAERN1AR | |
| SCHEMBL13840641 | 0.77 | CA2 (0.71) | CRHBPCRHR2CA1CA2MMP3 | |
| SCHEMBL28440862 | 0.76 | BACE1 (0.49) | KIF11HDAC6AKR1C2AKR1C1AR | |
| SCHEMBL4779653 | 0.76 | RXRA (0.58) | LDHAKIF11HDAC6ARALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | CRHBP 1604/4885CRHR2 470/4885LDHA 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.