Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503012 | 0.94 | MAPT (0.39) | ACACBMAPTFFAR2LMNATP53 | |
| SCHEMBL6496508 | 0.92 | FFAR2 (0.35) | NPSR1HPGDMAPTFFAR2LMNA | |
| SCHEMBL6496054 | 0.91 | KDM4E (0.40) | ACACBNPSR1HPGDMAPTTP53 | |
| SCHEMBL6495548 | 0.87 | TP53 (0.40) | ACACBNPSR1HPGDMAPTTP53 | |
| SCHEMBL6506148 | 0.87 | KMT2A (0.38) | ACACBFFAR2RXFP1MEN1KMT2A | |
| SCHEMBL6504635 | 0.85 | MAPT (0.47) | ACACBNPSR1HPGDMAPTLMNA | |
| SCHEMBL6495786 | 0.81 | NPC1 (0.38) | NPSR1LMNATP53NPC1RAB9A | |
| SCHEMBL6496229 | 0.78 | SHMT1 (0.36) | ACACBHPGDMAPTRXFP1MEN1 | |
| SCHEMBL7676306 | 0.77 | MAPT (0.42) | NPSR1HPGDMAPTLMNATP53 | |
| SCHEMBL6503799 | 0.76 | EGLN2 (0.35) | DGAT1ACACBMAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |