Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502426 | 0.83 | FFAR1 (0.42) | FFAR1PPARDCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6502683 | 0.83 | FFAR1 (0.48) | FFAR1PPARDCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6505456 | 0.78 | SLC13A5 (0.48) | FFAR1RXRARXRBFFAR4SLC13A5 | |
| SCHEMBL6507161 | 0.77 | RARB (0.46) | — | |
| SCHEMBL6502428 | 0.76 | FFAR1 (0.44) | FFAR1PPARDCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6499914 | 0.75 | CYP4F2 (0.55) | FFAR1 | |
| SCHEMBL6501062 | 0.73 | TYR (0.45) | — | |
| SCHEMBL6530111 | 0.73 | SRC (0.38) | FFAR1PPARDCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6502525 | 0.73 | CYP11B1 (0.47) | FFAR1PPARDCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6505023 | 0.71 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |