Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502688 | 0.83 | FFAR1 (0.48) | FFAR1PPARDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6505454 | 0.80 | ACACB (0.49) | FFAR1MTNR1AACACBACACARXRA | |
| SCHEMBL6507158 | 0.78 | RARB (0.45) | — | |
| SCHEMBL6502426 | 0.77 | FFAR1 (0.42) | FFAR1PPARDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6499912 | 0.76 | CYP4F2 (0.53) | FFAR1ACACB | |
| SCHEMBL6501058 | 0.75 | OPRM1 (0.47) | — | |
| SCHEMBL6505903 | 0.73 | MMP12 (0.64) | FFAR1ACACB | |
| SCHEMBL6502525 | 0.73 | CYP11B1 (0.47) | FFAR1PPARDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6505017 | 0.73 | MMP12 (0.51) | — | |
| SCHEMBL6502428 | 0.72 | FFAR1 (0.44) | FFAR1PPARDCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |