Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | ACACA | Q13085 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507161 | 0.83 | RARB (0.46) | PPARGPPARA | |
| SCHEMBL6530514 | 0.82 | FDFT1 (0.41) | SLC13A5FDFT1ACACBACACANR1H4 | |
| SCHEMBL6505454 | 0.82 | ACACB (0.49) | SLC13A5FDFT1ACACBACACANR1H4 | |
| SCHEMBL6502688 | 0.78 | FFAR1 (0.48) | SLC13A5ACACBACACARXRARXRB | |
| SCHEMBL6530516 | 0.76 | SLC13A5 (0.53) | SLC13A5FDFT1ACACBACACANR1H4 | |
| SCHEMBL9253929 | 0.75 | LMNA (0.58) | ACACBACACANR1H4PLA2G4BRXRA | |
| SCHEMBL6503746 | 0.75 | THRA (0.46) | — | |
| SCHEMBL6529916 | 0.75 | CYP2D6 (0.39) | NR1H4CYP2D6PTGESALOX5PPARG | |
| SCHEMBL23590265 | 0.75 | RXRA (0.59) | ACACBACACANR1H4PLA2G4BRXRA | |
| SCHEMBL2568516 | 0.73 | SMN1; SMN2 (0.53) | SLC13A5FDFT1NR1H4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |