Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296863 | 0.99 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL3433055 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1369159 | 0.80 | SUMO2 (0.40) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL560834 | 0.78 | CA1 (0.38) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL304685 | 0.76 | CA1 (0.38) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL304686 | 0.76 | CA1 (0.38) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1714853 | 0.76 | CASP6 (0.35) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1305294 | 0.71 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL28948590 | 0.71 | MEN1 (0.55) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL4296859 | 0.69 | MEN1 (0.56) | ALDH1A1MEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071388-B2 | Compositions and methods for biodetection by nucleic acid-templated chemistry | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090275142-A1 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE THERAPEUTICS CORPORATION | 2009-11-05 | — | — | US | disclosed |
| EP-2066813-A2 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | Ensemble Discovery Corporation (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008054600-A2 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE DISCOVERY CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275142-A1 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | POLRMT, NT5C3B, RNGTT | ALDH1A1 3803/4885MEN1 1957/4885KMT2A 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.