Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296989 | 0.99 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL3433055 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1369159 | 0.81 | SUMO2 (0.40) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL304685 | 0.77 | CA1 (0.38) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL304686 | 0.77 | CA1 (0.38) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1714853 | 0.77 | CASP6 (0.35) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL560834 | 0.76 | CA1 (0.38) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL1305294 | 0.72 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL4296859 | 0.70 | MEN1 (0.56) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL18794806 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180327357-A1 | NOVEL ORGANIC COMPOUND, NEAR-INFRARED FLUORESCENT CONSTANT MEDIUM CONTAINING SAME, AND METHOD FOR NANO-GRANULATING CONSTANT MEDIUM | CHAMEDITECH CO., LTD. (KR) | 2018-11-15 | — | — | US | disclosed |
| EP-3166606-B1 | FLUORESCENT CONJUGATES | SURGIMAB S A S (FR) | 2018-05-09 | — | — | EP | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
| US-9821079-B2 | Fluorescent conjugates | SURGIMAB S.A.S. (FR) | 2017-11-21 | — | — | US | disclosed |
| US-20170035915-A1 | FLUORESCENT CONJUGATES | SURGIMAB S.A.S. (FR) | 2017-02-09 | — | — | US | disclosed |
| WO-2016193396-A1 | FLUORESCENT CONJUGATES | SURGIMAB S.A.S. (FR) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016111602-A2 | NOVEL ORGANIC COMPOUND, NEAR-INFRARED FLUORESCENT CONSTANT MEDIUM CONTAINING SAME, AND METHOD FOR NANO-GRANULATING CONSTANT MEDIUM | 차의과학대학교 산학협력단 | 2016-07-14 | — | — | WO | disclosed |
| US-9273089-B2 | Composite probes and use thereof in super resolution methods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150073154-A1 | Discrete PEG Based Dyes | EQUIP, LLC (US) | 2015-03-12 | — | — | US | disclosed |
| US-8547533-B2 | Composite probes and use thereof in super resolution methods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-10-01 | — | — | US | disclosed |
| US-20090041670-A1 | Near Infrared Fluorescent Contrast Agent And Method For Fluorescence Imaging | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | disclosed |
| US-7473415-B2 | Near infrared fluorescent contrast agent and method for fluorescence imaging | FUJI PHOTO FILM CO., LTD. (JP) | 2009-01-06 | — | — | US | disclosed |
| EP-1480683-B1 | NEAR INFRARED FLUORESCENT CONTRAST AGENT AND METHOD FOR FLUORESCENCE IMAGING | FUJIFILM CORP (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2008054600-A2 | COMPOSITIONS AND METHODS FOR BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | ENSEMBLE DISCOVERY CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| US-7312326-B2 | Fluorescent labeled nucleotide derivatives | BECKMAN COULTER, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-0350026-B1 | Infrared filter dye for photographic element | EASTMAN KODAK CO (US) | 1994-10-12 | — | — | EP | disclosed |
| EP-0251282-B1 | NOVEL INFRARED ABSORBING DYES AND PHOTOGRAPHIC ELEMENTS CONTAINING SAME | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4933269-A | COOL IMAGE TONE | EASTMAN KODAK COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| US-4876181-A | ANTIHALATION, ANTISTAINING AGENTS; CYANINE DYES OF INDOLE, BENZINDOLE OR NAPHTHINDOLE TYPES | EASTMAN KODAK COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0251282-A2 | Novel infrared absorbing dyes and photographic elements containing same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090041670-A1 | Near Infrared Fluorescent Contrast Agent And Method For Fluorescence Imaging | ARG1, F12, CD68 | ALDH1A1 2706/4885MEN1 12/4885KMT2A 2967/4885 |
| US-20180327357-A1 | NOVEL ORGANIC COMPOUND, NEAR-INFRARED FLUORESCENT CONSTANT MEDIUM CONTAINING SAME, AND METHOD FOR NANO-GRANULATING CONSTANT MEDIUM | GRN, NPM1, NEFM | ALDH1A1 2660/4885MEN1 472/4885KMT2A 4175/4885 |
| US-20150073154-A1 | Discrete PEG Based Dyes | MKI67, MUC1, TP53 | ALDH1A1 958/4885MEN1 2840/4885KMT2A 4642/4885 |
| US-20170035915-A1 | FLUORESCENT CONJUGATES | MKI67, CD99, TPD52L2 | ALDH1A1 467/4885MEN1 122/4885KMT2A 1789/4885 |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | ALDH1A1 653/4885MEN1 541/4885KMT2A 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.