Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104408 | 0.80 | ALDH1A1 (0.55) | TSHRMEN1KMT2AKCNJ1KCNH2 | |
| SCHEMBL6504475 | 0.78 | TSHR (0.60) | TSHRKMT2AKCNJ1KCNH2LOXL2 | |
| SCHEMBL13946243 | 0.77 | CYP1A2 (0.67) | TSHRMEN1KMT2AKCNJ1KCNH2 | |
| SCHEMBL3292782 | 0.77 | TSHR (0.75) | TSHRKCNJ1KCNH2CYP1A2CYP2C19 | |
| SCHEMBL27583120 | 0.75 | ALDH1A1 (0.65) | TSHRMEN1KMT2AKCNJ1KCNH2 | |
| SCHEMBL3672572 | 0.75 | HSD11B1 (0.55) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL28299042 | 0.74 | CA12 (0.47) | TSHRMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL4661774 | 0.74 | CA2 (0.57) | MEN1KMT2ACYP1A2CYP2C19LOXL2 | |
| SCHEMBL4618998 | 0.74 | MMP2 (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11842004 | 0.72 | KMT2A (0.61) | MEN1KMT2AHTTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103035-A1 | MODIFIED FISCHER INDOLE SYNTHESIS OF ELETRIPTAN | PFIZER LIMITED (GB) | 2005-11-03 | — | — | WO | disclosed |