SCHEMBL650457

SCHEMBL650457

CCCCC(CC)(COC(=O)CC(C)=O)COC(=O)CC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.38
GAA P10253 2/20 0.38
SI P14410 2/20 0.38
MGAM2 Q2M2H8 2/20 0.38
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FAAH O00519 2/20 0.33
PAM P19021 2/20 0.33
NAAA Q02083 1/20 0.32
DGKA P23743 1/20 0.32
THRB P10828 1/20 0.31
PKM P14618 1/20 0.31
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CES2 O00748 2/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22050939 0.85 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL651229 0.85 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL30010780 0.82 ALDH1A1 (0.48) ALDH1A1MEN1MAPTKMT2AATM
SCHEMBL23041383 0.81 DGKA (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL11583984 0.81 HSD17B10 (0.34) ALDH1A1PAMNAAADGKATHRB
SCHEMBL7708371 0.80 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL22124844 0.80 THRB (0.42) MGAMGAASIMGAM2THRB
SCHEMBL8999875 0.80 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL15933340 0.80 NAAA (0.47) ALDH1A1MEN1MAPTKMT2AATM
SCHEMBL10406501 0.79 DGKA (0.56) ALDH1A1MEN1MAPTKMT2APAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12187923-B2 Michael-addition-hardening synthetic resin for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2025-01-07 US claimed
US-12180394-B2 Michael-addition-hardening hybrid system for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2024-12-31 US claimed
US-20230002653-A1 MICHAEL-ADDITION-HARDENING HYBRID SYSTEM FOR CHEMICAL FIXING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2023-01-05 US claimed
US-20220411680-A1 MICHAEL-ADDITION-HARDENING SYNTHETIC RESIN FOR CHEMICAL FIXING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2022-12-29 US claimed
CN-114729253-A Michael addition hardening synthetic resin for chemical fixing technology 费希尔厂有限责任两合公司 2022-07-08 CN claimed
CN-114729224-A Michael addition hardening hybrid system for chemical fixation technology 费希尔厂有限责任两合公司 2022-07-08 CN claimed
EP-0971989-B1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEM CO (US) 2008-02-27 EP claimed
US-RE39877-E1 Non-polymeric acetoacetates as adhesion promoting coalescing agents EASTMAN CHEMICAL COMPANY (US) 2007-10-09 US claimed
US-6187385-B1 For waterborne coatings applied to corroded or rusty metal substrates EASTMAN CHEMICAL COMPANY 2001-02-13 US claimed
EP-0971989-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 2000-01-19 EP claimed
US-5922790-A ACETOACETATE ESTERS AS ADDED TO WATERBORNE COMPOSITIONS CONTAINING ALKYD RESINS; IMPROVED ADHESION, ESPECIALLY TO CORRODED METAL SUBSTRATES EASTMAN CHEMICAL COMPANY (US) 1999-07-13 US claimed
WO-1998030639-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 1998-07-16 WO claimed
US-12187923-B2 Michael-addition-hardening synthetic resin for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2025-01-07 US disclosed
US-12180394-B2 Michael-addition-hardening hybrid system for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2024-12-31 US disclosed
US-11891537-B2 Triphenylphosphine-containing coatings with enhanced adhesion to unprimed surfaces SHEBOYGAN PAINT COMPANY (US) 2024-02-06 US disclosed
US-20230002653-A1 MICHAEL-ADDITION-HARDENING HYBRID SYSTEM FOR CHEMICAL FIXING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2023-01-05 US disclosed
US-6187385-B1 For waterborne coatings applied to corroded or rusty metal substrates EASTMAN CHEMICAL COMPANY 2001-02-13 US disclosed
EP-0971989-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 2000-01-19 EP disclosed
US-5922790-A ACETOACETATE ESTERS AS ADDED TO WATERBORNE COMPOSITIONS CONTAINING ALKYD RESINS; IMPROVED ADHESION, ESPECIALLY TO CORRODED METAL SUBSTRATES EASTMAN CHEMICAL COMPANY (US) 1999-07-13 US disclosed
WO-1998030639-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 1998-07-16 WO disclosed