Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507732 | 0.89 | RAB9A (0.47) | RAB9ANPC1MAPTALDH1A1MAPK1 | |
| SCHEMBL6507906 | 0.89 | S1PR1 (0.43) | S1PR1MAPTALDH1A1MAPK1PPARG | |
| SCHEMBL6507739 | 0.81 | GRM5 (0.42) | RAB9ANPC1MAPTPPARGPPARA | |
| SCHEMBL6533650 | 0.77 | MAOB (0.42) | S1PR1RAB9ANPC1MAPTESRRB | |
| SCHEMBL6510873 | 0.77 | PPARG (0.46) | S1PR1RAB9ANPC1PPARGPPARA | |
| SCHEMBL9734549 | 0.72 | CA1 (0.48) | ALDH1A1ESRRBL3MBTL1TDP1KMT2A | |
| SCHEMBL6505172 | 0.68 | ESR1 (0.47) | S1PR1PPARGPPARAL3MBTL1KMT2A | |
| SCHEMBL13057604 | 0.67 | ALDH1A1 (0.57) | RAB9ANPC1MAPTALDH1A1MAPK1 | |
| SCHEMBL12637601 | 0.67 | NPC1 (0.71) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL12137308 | 0.67 | NPC1 (0.71) | RAB9ANPC1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |