Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505176 | 0.89 | S1PR1 (0.43) | RAB9ANPC1MAPK1MAPTPPARG | |
| SCHEMBL6507906 | 0.88 | S1PR1 (0.43) | MAPK1MAPTGAASMN1; SMN2PPARG | |
| SCHEMBL6507739 | 0.80 | GRM5 (0.42) | RAB9ANPC1MAPTCYP1A2CYP2D6 | |
| SCHEMBL6510873 | 0.76 | PPARG (0.46) | RAB9ANPC1PPARGPPARAMAOB | |
| SCHEMBL6533650 | 0.76 | MAOB (0.42) | RAB9ANPC1MAPTGAASMN1; SMN2 | |
| SCHEMBL9453585 | 0.72 | ALDH1A1 (0.44) | RAB9ANPC1MAPTGAASMN1; SMN2 | |
| SCHEMBL9734549 | 0.71 | CA1 (0.48) | CYP1A2GFERCA1CA2CA9 | |
| SCHEMBL6510664 | 0.69 | ESR1 (0.46) | RAB9ANPC1MAPTPPARGPPARA | |
| SCHEMBL21991533 | 0.68 | L3MBTL1 (0.52) | RAB9ANPC1MAPTGAAMEN1 | |
| SCHEMBL6153847 | 0.67 | GAA (0.46) | RAB9AMAPK1MAPTGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |