Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507906 | 0.87 | S1PR1 (0.43) | PPARGPPARAMAOBS1PR1NR4A2 | |
| SCHEMBL6507739 | 0.81 | GRM5 (0.42) | PPARGPPARAMAOBNR4A2NPC1 | |
| SCHEMBL6505176 | 0.77 | S1PR1 (0.43) | PPARGPPARAMAOBS1PR1NPC1 | |
| SCHEMBL6507732 | 0.76 | RAB9A (0.47) | PPARGPPARAMAOBNPC1MEN1 | |
| SCHEMBL6533650 | 0.74 | MAOB (0.42) | MAOBS1PR1NPC1RAB9A | |
| SCHEMBL6510871 | 0.71 | PPARG (0.51) | PPARGPPARAMAOBS1PR1CA12 | |
| SCHEMBL6511131 | 0.69 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL6511136 | 0.69 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL15560833 | 0.65 | PPARG (0.44) | PPARGPPARAMAOBNR4A2CA12 | |
| SCHEMBL6155864 | 0.65 | KMT2A (0.48) | PPARGMAOBCA12NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |