Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503874 | 0.89 | KMT2A (0.36) | KMT2AAGTR1ALDH1A1HPGD | |
| SCHEMBL6506231 | 0.82 | KMT2A (0.37) | KMT2AMAPTHTTRAB9AALDH1A1 | |
| SCHEMBL6510626 | 0.81 | TDP1 (0.34) | KMT2ASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL6505095 | 0.81 | KDM4E (0.32) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6501528 | 0.80 | L3MBTL1 (0.36) | MAPTNPSR1NPC1RAB9ALMNA | |
| SCHEMBL6499622 | 0.80 | HPGD (0.35) | KMT2AMAPTHTTNPSR1NPC1 | |
| SCHEMBL6499218 | 0.79 | LMNA (0.35) | KMT2ANPSR1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL6501686 | 0.79 | NPSR1 (0.39) | KMT2AMAPTHTTNPSR1NPC1 | |
| Trifluoroacetic Acid SCHEMBL6504699 | 0.79 | — | — | |
| SCHEMBL6508566 | 0.78 | ALDH1A1 (0.38) | KMT2AMAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | KMT2A 3213/4885AGTR1 343/4885MAPT 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.