Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 6/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESRRG | P62508 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | FADS1 | O60427 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514861 | 0.81 | DYRK1A (0.52) | IKBKBJAK2JAK3NPC1MAPT | |
| SCHEMBL6509836 | 0.76 | HSD17B1 (0.48) | IKBKBMEN1KMT2AJAK2JAK3 | |
| SCHEMBL167193 | 0.76 | MEN1 (0.71) | MEN1KMT2AFADS1KDM4EHSD17B10 | |
| SCHEMBL6506340 | 0.75 | FLT3 (0.51) | IKBKBMEN1KMT2AKDM4EJAK2 | |
| Ammonia Solution, Strong SCHEMBL28790660 | 0.74 | MEN1 (0.69) | MEN1KMT2AFADS1KDM4EHSD17B10 | |
| SCHEMBL6507152 | 0.74 | IKBKB (0.57) | IKBKBMEN1KMT2AJAK2JAK3 | |
| SCHEMBL6514837 | 0.74 | CHEK1 (0.47) | IKBKBMEN1KMT2AKDM4EJAK2 | |
| SCHEMBL6511844 | 0.74 | CYP2C19 (0.51) | IKBKBMEN1KMT2AKDM4EJAK2 | |
| SCHEMBL6530703 | 0.72 | IKBKB (0.51) | IKBKBMEN1KMT2AJAK2JAK3 | |
| SCHEMBL6505865 | 0.72 | IKBKB (0.58) | IKBKBMEN1KMT2AJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |