Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.44 |
| ▸ | ACHE | P22303 | 11/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511304 | 0.80 | MAPT (0.45) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL5923412 | 0.80 | BCHE (0.42) | BCHEACHESLC2A1SMN1; SMN2KMT2A | |
| SCHEMBL6510702 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AMEN1MAPK1MAPT | |
| SCHEMBL6514076 | 0.76 | ADORA2A (0.52) | BCHEACHESMN1; SMN2KMT2AMAPT | |
| SCHEMBL6511110 | 0.75 | SIGMAR1 (0.41) | SMN1; SMN2 | |
| SCHEMBL6509392 | 0.73 | MAPT (0.43) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL6508660 | 0.71 | MAPK1 (0.52) | SMN1; SMN2KMT2AMEN1MAPK1MAPT | |
| SCHEMBL10501448 | 0.71 | CYP1A2 (0.49) | SMN1; SMN2KMT2AMEN1MAPK1LMNA | |
| SCHEMBL10501444 | 0.71 | CYP1A2 (0.49) | SMN1; SMN2KMT2AMEN1MAPK1LMNA | |
| SCHEMBL6513739 | 0.71 | SMN1; SMN2 (0.42) | ACHESMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |