Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528363 | 0.82 | MAPT (0.38) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL6509349 | 0.75 | TP53 (0.36) | MAPTLMNAKMT2AHPGDTP53 | |
| SCHEMBL6681282 | 0.73 | TSHR (0.43) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL6678323 | 0.71 | HTR1A (0.42) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL6507803 | 0.70 | ALDH1A1 (0.40) | TSHRKMT2AHPGDTP53ALDH1A1 | |
| SCHEMBL6681524 | 0.69 | MAPT (0.47) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL6532464 | 0.69 | PPARA (0.54) | — | |
| SCHEMBL6531482 | 0.68 | PPARG (0.45) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL5668943 | 0.67 | TSHR (0.44) | MAPTLMNARXFP1TSHRKMT2A | |
| SCHEMBL15157526 | 0.67 | KMT2A (0.60) | MAPTLMNARXFP1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | claimed |
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | disclosed |