SCHEMBL6512683

SCHEMBL6512683

Cc1ccc(Cc2cccc(CN(CCC(=O)O)Cc3cccc(C)c3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 3/20 0.46
SAE1 Q9UBE0 1/20 0.43
UBA2 Q9UBT2 1/20 0.43
FFAR4 Q5NUL3 1/20 0.42
LTA4H P09960 2/20 0.41
FFAR1 O14842 3/20 0.40
CSF1R P07333 2/20 0.40
EGFR P00533 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
HSP90AA1 P07900 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.39
PTGES O14684 1/20 0.39
NR1H4 Q96RI1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512357 0.95 TAS2R14 (0.43) MEP1BSAE1UBA2FFAR4LTA4H
SCHEMBL6513388 0.92 MEP1B (0.46) MEP1BSAE1UBA2FFAR4LTA4H
SCHEMBL6516556 0.91 LTA4H (0.45) MEP1BSAE1UBA2FFAR4LTA4H
SCHEMBL6510755 0.89 MEP1B (0.56) MEP1BLTA4HFFAR1NPC1RAB9A
SCHEMBL6511925 0.88 HTT (0.51) MEP1BSAE1UBA2FFAR4FFAR1
SCHEMBL6513938 0.88 PKM (0.44) MEP1BFFAR1CSF1REGFRHSP90AA1
SCHEMBL6508483 0.88 TSHR (0.45) MEP1BFFAR4FFAR1THRATHRB
SCHEMBL6510202 0.86 NPC1 (0.41) MEP1BLTA4HNPC1RAB9AL3MBTL1
SCHEMBL6511127 0.86 PKM (0.38) MEP1BFFAR4FFAR1CSF1REGFR
SCHEMBL6509563 0.85 CALM1 (0.51) MEP1BFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005097100-A2 ANTIBACTERIAL AGENTS PROLYSIS LTD. (GB) 2005-10-20 WO disclosed