Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.63 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.63 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.62 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.60 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508605 | 1.00 | MAOB (0.65) | MAOBMAOAS1PR1S1PR5SPHK1 | |
| SCHEMBL6167500 | 0.90 | MAOB (0.79) | MAOBMAOAS1PR1S1PR5SPHK1 | |
| SCHEMBL6167507 | 0.90 | MAOB (0.79) | MAOBMAOAS1PR1S1PR5SPHK1 | |
| SCHEMBL6171507 | 0.88 | MAOA (0.61) | MAOBMAOAS1PR1S1PR5SPHK1 | |
| SCHEMBL3148367 | 0.87 | NPBWR1 (0.53) | SPHK1CD274PDCD1 | |
| SCHEMBL1815987 | 0.87 | NPBWR1 (0.53) | SPHK1CD274PDCD1 | |
| SCHEMBL2030130 | 0.87 | NPBWR1 (0.53) | SPHK1CD274PDCD1 | |
| SCHEMBL6171239 | 0.87 | MAOB (0.74) | MAOBMAOAS1PR1S1PR5SPHK1 | |
| SCHEMBL6171245 | 0.87 | MAOB (0.74) | MAOBMAOAS1PR1S1PR5SPHK1 | |
| SCHEMBL7814221 | 0.84 | NPBWR1 (0.58) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |