Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 15/20 | 0.73 |
| ▸ | SLC6A5 | Q9Y345 | 12/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917370 | 0.84 | SLC6A9 (1.00) | SLC6A9SLC6A5SMN1; SMN2 | |
| SCHEMBL3929509 | 0.82 | SLC6A5 (0.86) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL4428759 | 0.81 | MAPT (0.66) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL6505622 | 0.81 | SLC6A9 (0.63) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL3925116 | 0.79 | SLC6A5 (0.79) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL3927647 | 0.78 | SLC6A5 (0.78) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL3928898 | 0.78 | SLC6A5 (0.78) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL3931232 | 0.78 | SLC6A5 (1.00) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| Ammonia Solution, Strong SCHEMBL3929225 | 0.78 | SLC6A5 (0.78) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 | |
| SCHEMBL6955366 | 0.78 | ALDH1A1 (0.71) | SLC6A9SLC6A5ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070539-A1 | Benzoyl-piperazine derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070539-A1 | Benzoyl-piperazine derivatives | OPRL1, ACHE, PNMT | SLC6A9 4305/4885SLC6A5 2174/4885ALDH1A1 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.